ISSN 1662-4009 (online)

ey0018.15-7 | (1) | ESPEYB18

15.7. A placebo-controlled trial of subcutaneous semaglutide in nonalcoholic steatohepatitis

Newsome Philip N , Buchholtz Kristine , Cusi Kenneth , Linder Martin , Okanoue Takeshi , Ratziu Vlad , Sanyal Arun J , Sejling Anne-Sophie , Harrison Stephen A

N Engl J Med 2021; 384:1113–1124. DOI: 10.1056/NEJMoa2028395 https://www.nejm.org/doi/full/10.1056/NEJMoa2028395The authors report a 72-week, double-blind placebo-controlled trial in 320 adult patients with biopsy-confirmed nonalcoholic steatohepatitis (NASH) and liver fibrosis (stage F1, F2, or F3). Patients were randomly assig...